How to live longer: Calorie restriction lowers free radicals reducing cancer risk

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Analyses included traditional diet composition, energy intake, energy expenditure, mortality from age-related diseases, and current survival patterns.

Findings include low caloric intake and negative energy balance at younger ages, little weight gain with age, life-long low BMI, relatively high plasma DHEA levels at older ages, low risk for mortality from age-related diseases, and survival patterns consistent with extended mean and maximum life span.

It concluded that: “This study lends epidemiologic support for phenotypic benefits of CR in humans and is consistent with the well-known literature on animals with regard to CR phenotypes and healthy ageing.”

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