As the cells die, their contents enter the bloodstream, which prevents the kidneys from removing waste and concentrated urine.
According to the National Institute for Health and Care Excellence: “Muscle toxicity can occur with all statins, however, the likelihood increases with higher doses and in certain patients.
“Statins should be used with caution in patients at increased risk of muscle toxicity, including those with a personal or family history of muscular disorders, previous history of muscular toxicity, a high alcohol intake, renal impairment or hypothyroidism.
“In patients at increased risk of muscle effects, a statin should not usually be started if the baseline creatine kinase concentration is more than five times the upper limit or normal.