Important Tests to Undertake to Detect Dangerous Diseases like AIDS

Early detection allows for timely intervention, enabling individuals to seek appropriate medical care and adopt preventive measures to protect their health and well-being.

Dr Janakiram Bobbillapati, HOD Molecular Biology, Microbiology & Serology at TRUSTlab Diagnostics shares the tests one should undertake for the diagnosis of dangerous diseases

Early detection of diseases like AIDS (Acquired Immunodeficiency Syndrome) is crucial for effective treatment and management. Regular health screenings, including specific tests, can play a significant role in identifying potential health concerns before they progress.

  1. A Complete Blood Count (CBC) test offers valuable insights into various blood components, such as red blood cells, white blood cells, and platelets. A low white blood cell count (lymphocytes) detected in the CBC test may indicate a compromised immune system, prompting further investigation.
  2. HIV P24 Antigen Test:The HIV p24 antigen is the most abundant HIV protein and is essential for assembly of the capsid that encases HIV genetic material. Detection of the HIV p24 antigen is used clinically to diagnose early HIV infection, during which HIV-specific antibodies are not yet detectable.
  3. HIV Antibody by ELISA/CLIAFollowing an indication from the P24 antigen test, the next step is often an HIV Antibody Test, the primary screening tool for detecting HIV infection. This test identifies antibodies produced by the body in response to the HIV virus. While results typically become positive within a few weeks to months after exposure, they provide crucial information for early intervention.For individuals requiring rapid results or facing inconclusive initial tests, the Rapid HIV Test is recommended. Similar to the standard antibody test, it checks for HIV antibodies but provides results within 20-30 minutes, enabling immediate counseling and decision-making.
  4. The Fourth-Generation HIV Test, also known as the Combination or Duo Test, goes beyond antibody detection by identifying both HIV antibodies and antigens. This test offers earlier detection compared to standard antibody tests, potentially identifying HIV infection within two to three weeks after exposure.In situations where early detection is critical, the HIV RNA Test, or nucleic acid test (NAT) by RT-PCR, becomes invaluable. Highly sensitive, it detects HIV RNA in the blood within days to weeks after exposure, providing the earliest available detection of HIV infection.In addition to HIV-specific tests, regular screening for sexually transmitted infections (STIs) is essential. Many STIs, including syphilis and gonorrhea, can increase the risk of HIV transmission. STI screening, which may involve urethral discharges screening tests, swab tests, or blood tests, is an integral part of preventive healthcare.

    In conclusion, regular health screenings, avoiding multiple sexual partners, maintaining sexual hygiene and specific tests are vital for early detection of dangerous diseases like AIDS. Tests such as the P24 Antigen and HIV RNA by RT-PCR provide initial indicators of potential health concerns, prompting further testing for HIV/AIDS and related symptoms. Early detection allows for timely intervention, enabling individuals to seek appropriate medical care and adopt preventive measures to protect their health and well-being. Remember, early detection saves lives.

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