B12 deficiency: Man, 22, seeks medical help after hyperpigmentation strikes knuckles

“His body mass index was 20, and his weight had been stable over the past 12 months.”

Following tests, he was diagnosed with one of the “rare” early manifestations of vitamin B12 deficiency.

“As all other causes for hyperpigmentation were ruled out other than low serum vitamin B12 levels,” the study adds.

He was treated with B12 injections twice a week for a month plus tablet supplements daily.

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